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Showing posts with label genetics. Show all posts
Showing posts with label genetics. Show all posts

Saturday, March 25, 2017

As The Old Jewish Saying Goes, And As I've Lived Especially Of Late...

What's keeping calm when you're Jewish? What's not worrying when you're Jewish?

As for me and being a Jewish Christian, I get the whole "Do not worry", "Come to Me, you whom are weary...", "Cast your cares...", etc.. Notwithstanding that (and here goes the "Oh, you of little faith"):

  1. Having Cerebral Palsy and IBS affects worry for good reason.
  2. Having OCD/Anxiety and ADD affects worry for good reason. By the way, I'm actually not the first one to have made an observation regarding whether OCD/Anxiety is inherently Jewish, and I was joking about that more to cope with my own OCD and wondering (so much for Jewish humor, as I got a hard time for making that observation)—the schtick about (I kid you not) OCD being a "Jewish disease" (as Dr. Avigdor Bonchek phrased the schtick whether OCD is Jewish) has been around for a long time. To be fair, look at, e.g., B'midbar 7 alone—having to be perfectly scrupulous about the right number of the right offerings like that could cause anyone to worry—then look at Vaiykra 11 and B'midbar 19—I myself (assuming that I'd survived birth and even had some part in Jewish life) would be washing and extra washing all day. Then try the fences around Torah. Overtime, that has to get embedded into one's genetic code and/or brain chemistry—thus, I think, part of why God desires mercy over sacrifice and obedience over burnt offerings, as His point seemed to be that ritualism as opposed to simply living by faith (e.g., "walk[ing] humbly with your God").
  3. Getting the amount of hate that I get (as I probably will over the observation above, for example), whether rightly or wrongly, affects me to always worry for good reason—even, e.g., who's going to unfriend me on Facebook or unfollow me on Twitter, thus reflecting online how what they think of me both online and offline? After all (as Curt Schilling of all people stated), people online are who they are offline and what they would be offline "if they could get away with it" (which he stated after two of his daughter's high-school classmates used Twitter to send her rape threats.
I could give more examples, though I think that three examples suffice—especially as I brace myself and bide to see how many more instances of Example Three will happen even over the next couple of minutes, especially in regard to Example Two. 

Monday, December 12, 2016

Without Trying To Be Funny, Crude, Or Ugly...

I have to ask what will happen if Trump ends up getting Alzheimer's Disease and does end up becoming POTUS (with "P" being "Premier" at the still-bad best, and the "P" being replaced altogether by an "F" at worst).

After all, Trump's father died of Alzheimer's; and I'm sadly pretty sure that Alzheimer's made Fred Trump worse—and let's face that  Alzheimer's, which even affected my stepgrandfather to (for example) call his beloved wife a "dumb bunny", can affect or increase negative behavior (and my stepgrandfather had never verbally abused or otherwise mistreated her before he had Alzheimer's, by the way).

Can you imagine, then, what will happen if Donald Trump becomes POTUS and has Alzheimer's while he's in office—as if his behavior isn't bad enough without his having Alzheimer's? By the way, one reason to hope that reincarnation is not real is the possibility that Barron Trump—or anyone else—would be Fred Trump reincarnated!

Meanwhile, here's—sadly—an example of how erratic someone with Alzheimer's can act as they deal with being ravaged by Alzheimer's:

In conclusion, therefore, I ask you to think about what the Fred Trump-inspired son of Fred Trump will do if he's inherited his father's Alzheimer's and it ever sets him off—after all, it's set off good men like my late stepgrandather and the late Bob Murrell—imagine if it sets off the already-racist, -sexist, -xenophobic, -ableist, -nepotistic, -sociopathic, -dictatorial, and -Anti-Semitic Donald Trump—bad men + Alzheimer's Disease = bad combinations!

Tuesday, June 7, 2016

Why Cancer Survivor Day Is Not (As Cynics Would Allege) Just Another Cancer Lobby Hallmark Holiday

A friend made me aware that today is Cancer Survivor Day and asked that I make others aware of it. I'd be remiss to not do so, given that cancers of all kinds are in my gene pool and in my family otherwise—I have a BRCA mutation for example; and people thought that I was being funny or whatever—they can ask Katherine Czarnecki Chokola, z"l; she died of Breast Cancer. They can ask her cousin Tony's son Jack, whom survived Colon Cancer and later died of Leukemia (partly because, I'm sure, the Colon Cancer affected him despite that he survived it).

With that, Dad has Chron's (which is linked to Colon Cancer) and I have IBS (and I do not buy for a second that IBS and Chron's are not linked). Point being, I am well aware that cancer is not a game, gimmick, joke, etc.; and I would have never claimed to have a BRCA mutation were the evidence of it not in my own family line. By the way, part of why I volunteer for the Bladder Cancer Advocacy Network is because of the medical history of cancer in my family, not to mention that Bladder Cancer patient Kevin Williamson (who takes the newly-discovered drug to treat Bladder Cancer) had "unbearable gas" that made him aware of his Bladder Cancer (and with IBS, gas and the bladder are linked—so, imagine adding Bladder Cancer to that!)

That's also something about which I ask people to think on Cancer Survivor Day: those charities, walk-a-thons, etc. are not games, gimmicks, jokes, etc.

By the way, I just remembered: Michael Douglas is a cancer survivor, given that he had Throat/Oral/whatever kind of cancer; and his father had some kind of cancer, too (So's being a Danilovich—and I've discussed that whole megillah before!).

Tuesday, October 6, 2015

Something To Make Your Own and Share

I saw this on a Facebook friend's status, and I decided to personalize it. This isn't stuff that I haven't talked about in some capacity before, by the way. Incidentally, Great-Granddad Czarnecki could have (if God willed) lived to be 111 this month (October 24th) had he not committed suicide (Trust me; he has a certain cousin whom is 98 and will, if God wills, be 99 this year. He could easily have had that longevity gene, and only God knows if he did.).

Do me a favor, then, and make the following your own in a Facebook status, note, or something:

Depression is real and relentless. I and others have been on that edge, and I myself ended up in Sheppard Pratt over it in April of 2006 (To hide that is useless, especially when why the Depression was exacerbated affected me to threaten myself.). I'm therefore asking everyone to stop hiding their own Depression or whatever mental illness(es) you have (I also have, e.g., OCD, by the way.).

On the other hand, you can continue to hide it as many in my family have hidden it and did hide it—and let's see how well that works for you. Let me give you a hint: it doesn't work—if, for example, my father's paternal grandfather (Anthony Czarnecki, RIP) and maternal great-granduncles Alexander and Frank Fosko (z"l) could come back, they'd tell you.

So would their father, Istvan Foczko (z"l)—he was in his 50s when he died, had six sons and one daughter, and has never had his cause of death mentioned. Statistically, there is no other possibility that he died in any other way than by suicide—whether 29% of a chance (since two of his seven children committed suicide, and if you round the percentage up) or 66% (since two of his six sons committed suicide) the chance is well above 10%, and even 25%. The average of 29 and 66 is 47.5—so, think about that: almost 50% of a chance that he committed suicide, and the other 50-53% (that he didn't commit suicide, and that he even would have lived past his 50s) may well have happened if he had talked about what he endured. 

Meanwhile, I'm asking everyone to copy and paste this status—and personalize it. If only I was sharing a personal struggle with mental illness, it'd be a damned shame. Besides, you don't know whom you might help if you (in the words of my father's paternal grandmother, z"l) "talk about it" (When she broke down and told my aunt about many things before she died, those were her exact words after 90-plus years of life—"No; no, it's okay: I want to talk about it."). ♥

Sunday, April 19, 2015

By the Way, Kibosh the Khazar Theory Altogether

When I talked to the website owner of and asked him about the testing of Khazar skeletons, I received the following reply, in part:

Why are we still talking about the Khazars? They aren't involved inour ancestry at all and archaeologists and historians say it may bedifficult to distinguish Khazars proper from the other peoples of Khazaria,plus I'm not aware of anybody who has tested Khazar skeletons or plans to, butyou are welcome to ask around now that Russians have successfully testedmany populations like the Yamnaya and the Mal'ta.Based on the latest evidence I would say the Khazars are Volga Finnicintermixed with East-Central Asian Turks and other assorted peoples, andtheir Turkic element is the same one found in other Turks and Mongoliansaround Eurasia, a particular affinity never found in Ashkenazim....In lieu of ancient DNA, modern populationshave proven to be good proxies to determine ethnicity. Did you see my recentarticle "The Chinese Lady who Joined the AshkenazicPeople"? Ashkenazim are also descended from a Korean-related people, from amore recent Asian-Ashkenazic marriage.
Also by the way, I compare Dr. Himladevi "Himla" Soodyall to "Dr." Eran Elhaik. I don't know what agenda "Dr." Soodyall has, although I can ascertain that she attempted to delegitimize the Lemba as much as "Dr." Elhaik attempted to delegitimize Ashkenazi Jews.

PS My dad's Ancestry atDNA in even Analysis 2.0* does, in fact, show a very-slight amount of Middle Eastern atDNA. It also shows a tiny bit of East Asian, Melanesian, Scandinavian, and Finnish/Northwest Russian atDNA. The Melanesian atDNA is probably related to the East Asian atDNA, and Scandinavian atDNA to the Finnish/Northwest Russian atDNA.

*"We create estimates for your genetic ethnicity by comparing your DNA to the DNA of other people who are native to a region. The AncestryDNA reference panel (version 2.0) contains 3,000 DNA samples from people in 26 global regions."
The AncestryDNA panel does need to be balanced**, though:

The updated AncestryDNA ethnicity estimation V2 reference panel contains 3,000 samples carefully selected as described to represent 26 distinct global regions (Table 3.1), each with a somewhat distinct genetic profile. As a comparison, our Beta panel represented only 22 distinct global regions.

Region# Samples
Great Britain111
Europe East432
Iberian Peninsula81
European Jewish189
Europe West166
Finland/Northwest Russia59
Africa Southeastern Bantu18
Africa North26
Africa South-Central Hunter-Gatherers35
Ivory Coast/Ghana99
Native American131
Asia Central26
Asia East394
Asia South161
Near East141
Table 3.1: The Final AncestryDNA V2 Ethnicity Reference Panel

Regional Polygon Construction

As described above, we divide the globe into 26 overlapping geographic regions. Each region represents a population with a somewhat distinct genetic profile. Where possible, we use the known geographic locations of our samples to guide the delineation of regional boundaries. Figure 3.6 shows an example of the information used to define regional polygons.

For a more-accurate panel, they should have 115-16 ("115.384615"). Also, the selection should not be "carefully selected as described". The selection needs to be as random as possible. This cannot be accepted:

Before using the reference set to estimate ethnicities of AncestryDNA customers, we perform several experiments to lend support to the quality of this new reference set. This involves testing the performance of our ethnicity estimation procedure on the reference set of samples. (See Section 4 below for details regarding the statistical method used for ethnicity estimation.)
First, we use the new panel to do a leave-one-out analysis. In this experiment, we remove one sample from the reference panel and then use the remaining panel to estimate the ethnicity of the sample that has been removed. We repeat this process for every sample in the panel and then look at the average predicted ethnicity for each region in the set. Figure 3.4 shows the results of this experiment as a box plot.

Figure 3.4: Leave-one-out analysis of the V2 reference panel. Here we plot the results of an experiment in which each sample is removed from the reference set one-by-one and its ethnicity is estimated using the remaining panel samples. Each bar represents the average correctly predicted ethnicity for all samples from a given region. It is clear from this graph that for the majority of samples in each region, we predict at least 80% of the genetic ethnicity to be from the correct region. However, there are exceptions. In particular, our average prediction accuracy for samples from Great Britain, Western Europe, Iberian Peninsula, and Mali are not quite as high. There are many factors affecting the accuracy of these numbers, most importantly the number of reference samples in the panel for each region and the genetic distinctness of each region.

The purpose of this analysis is twofold. First, reference panel samples with poor performance in the leave-one-out analysis were removed. This included samples from individuals whose leave-one-out ethnicity did not represent their ethnic group of origin. (See for instance, Figure 3.5) Second, the leave-one-out plots allow us to define population boundaries and demonstrate our ability to accurately estimate the ethnicities of our reference panel samples using our method (see next section).

Figure 3.5: Removing Reference Panel Candidates. Leave-one-out estimation for a Reference Panel Candidate with 8 terminal ancestors from the Ivory Coast and Ghana region. While this sample was initially included as a candidate of the reference panel for the Ivory Coast/Ghana region, the sample’s leave-one-out ethnicity estimation reveals primarily Benin/Togo ancestry. As a result, this sample was removed from the reference panel.
In scientific studies, this is unacceptable unless it is for case studies and/or other non-generalizable/non-extrapolatable studies:

There are two sources of error that limit generalizability: sampling error (chance variation) and sample bias (constant error) which results from inadequate research design. Sampling error (but not sample bias) can be taken into account using statistics.
Probability samples are representative of the population. They permit generalization to the population from which they are drawn. There are two types of probability samples: Random and stratified.
Random - each individual in the population has an equal chance of being selected for the sample.
Stratified - a miniature representation of the larger population with regard to proportions within selected strata (e.g., gender, education, socioeconomic level). Individuals are randomly selected within strata.
table of random numbers or the random number function in Excel can be used to select a random sample from a population.
If a sample is, thus, "poor", it should be put in an "Indeterminable" or a "Poor Sample" category. 

Some would argue, "Well, what about other studies that don't have very-balanced numbers"? Given that numerous studies on Ashkenazi Jews, Lemba Jews, and other groups have been done overtime—and most have shown similar or equal results—the studies balance the numbers at least somewhat in the end. Therefore, the argument about "other studies that don't have very-balanced numbers" is moot at this point.

 ** Stratified Sampling – This technique divides the population into meaningful homogenous or similar groups based on a certain characteristic (e.g., gender, race, socioeconomic status) and then selects a simple random sample from each group. [For example, if you were interested in the affects of student motivation on academic achievement, particularly by grade level, you would divide the population into their respective grade levels and then randomly select an equal number of 9th, 10th, 11th, and 12th graders.]


Sunday, January 18, 2015

If Some Of You All Want To Keep Judging Ms. Dorvilier....

By the way, Google it, too. "Postpartum Depression violence". Some of you all need to grow up (at best) and/or get mental-health treatment (at "worst"/most). Also, do not buy that Postpartum Depression and violence have no link. Depression, let alone Postpartum Depression, can affect violence (including murder and murder-suicide). My father's paternal grandfather (not a Postpartum-Depressive man, let alone an untreated one, as far as I know) committed suicide because of Depression alone! How much more might a Postpartum-Depressive woman commit suicide and/or murder! In addition, I suggest that you keep silent if you have no clue about mental illness. After all, "Even a fool, when he holdeth his peace, is counted wise: and he that shutteth his lips is esteemed a man of understanding." (Proverbs 17:28, for Christians and so-called Christians—especially if you are Jewish. You well know that our fathers and mothers received all of Tanakh by the Second Temple Era). For everyone else, "Better to remain silent and be thought a fool than to speak out and remove all doubt."

Let me add, too, that I know about mental illness. I already explained enough about my mother's maternal grandmother's mother, did I not? I also explained enough my father's grandfather. Well, guess what? I inherited his Depression! I also inherited my father's OCD/Anxiety and ADD (He will admit to the ADD. He has yet to admit that OCD/Anxiety and Depression; though I clearly inherited his mental illnesses, and I remember those pill bottles that I saw in his now-former apartment. Let me tell you, now I know that not all of them were Vitamin B12 pills. I also have other memories that I did not think about at the time that they were present events.).

I, thus, know what I am saying. Therefore, I can open my mouth. I forgot to mention as well, and let me add, that my mother's paternal grandfather's father ended up in Springfield State Hospital due to Alcoholism. I also ended up in Sheppard Pratt once, and that's where I was diagnosed with Depression. I can give other examples as well, and now I am really going to tell the "some of you all" to shut your mouths and not say a damned thing about me—and I know that at least one of you thought that I was the fool in this case. I did not say that I am wise, by the way; so, you word twisters can really stop now (Do not think that I am clueless, either.).

I even suspect that quite a few of the "some of you all" are sociopaths and/or otherwise lacking compassion, critical thinking skills, and discernment as well. According to Fox News (who published an Associated Press article), "Authorities believe the mother doused her baby with an accelerant then set her on fire, Bewley said. They do not have a motive. The woman was taken into custody Friday night." Yet, some of you all have the hutzpah to cite "innocent until proven guilty" even in cases in which the motive is clear.

Postpartum Psychosis, Crime, Etc.

BTW, my sister wants to clarify that her rude background laughter had nothing to do with the subjects at hand, despite that I asked that she would be quiet while I made the video to which this blog entry applies.

Anyway, here are the statistics on Postpartum Depression and Psychosis:



(Please note that Black and other Non-White, Non-Hispanic women are affected the most.).



The original story is at

Tuesday, February 11, 2014

My Natural Look With Full Disclosure About Lighting, And...

Why do I care about my natural look? Some people at wanted to see non-blurry pictures of me to see whether or not I truly look Polish, which I don't (Thank God. :-) ) But hopefully, this helps them and others see that I truly look Jewish. They did concede that I look Western European, though. e.g.:

"Nicki - I'd say you look Spanish or Portuguese. Or maybe Italian? :-) But definitely South/Western European. Also, it's totally not true that ethnic Poles are blonde and blue-eyed - most Poles tend to have various shades of brown(ish) hair and can have all possible eye colours, often grey or brown. Many Polish women dye their hair blonde and that might have fooled you ;-) Of course, many people are blonde, but it's not the standard by any stretch of the imagination. Darker skin tones are not totally uncommon either. Either way, if you lived in Poland you would probably be seen as somewhat "exotic", people would tend to think you have some Spanish or Italian blood, but they would not automatically assume that you were not Polish. The Polish nation is very mixed - the Tartars and Turks, the Italians (Queen Bona), the Dutch (builders of the Żuławy Wiślane dyke system), the French (Napoleonic wars) and many others came to Poland in various periods and settled there :-)"

Remember "John McCoy"? Also, Mom is mostly Western European (Frankish, Gaelic, and Briton) with Ashkenazi Jewish heritage (the Siedenburg-Mueller and Lehr Pundts, for example—and possibly the Farrells, since Native Irish are light-eyed brunettes and the Farrells had red hair. But don't tell, e.g., my cousin Colleen DeBoy that—she got mad when I suggested that the red-haired Farrells (at least on our side), who (for Irish Catholics) had no children named Mary (for instance), may have been Irish Anusim. I can't change science or history, and Ya'akov (z"l) and Esav did have red hair.

PS Unless Sharon can show me the proof that the Farrells had a daughter named Mary, I don't buy it. There was no Mary who was born in 1857 who was recorded on the 1860 Census. Also, she could've been named for her mother (Mary Cassilly O'Farrell) if she did exist.

Monday, October 14, 2013

Noah's Haplogroup And More Proof That Ashkenazi Jews Are Not Khazars

"“These men and the Iceman had the same ancestors.”" So, 5773-5300 = 473 AM. The Flood happened in 2150 BCE (1610 years after creation, or 1610 AM). So, the man lived prior to the Flood. Noah had G-L91, then. The other haplogroups didn't come around until Babel.

As far as Ashkenazim:

As far as the "mosaic" aspect:

"Neither shall thy name any more be called Abram, but thy name shall be Abraham; for the father of a multitude of nations have I made thee6 And I will make thee exceeding fruitful, and I will make nations of thee, and kings shall come out of thee."


"[O]f them also will I take for the priests and for the Levites, saith the LORD."

By the way, they clearly admitted to limitations in the study. e.g.:

"In some cases, we could not recognize the ethno-ancestral characteristic of a specific haplotype; further comprehensive testing would accomplish this task. The detection of additional SNPs, testing for extended STR markers, and full mtDNA testing would help us to get a better understanding of the subjects of our investigation. Analysis of the autosomal DNA is another technique that would provide valuable inputs on this topic. Therefore, our study should be viewed as only a starting point for the analysis of this people."


"We sampled 23 East European Karaite men and 5 East European Karaite women: a total of 28 individuals with deep roots in the East European Karaite communities. We also sampled one Karaite man whose family had immigrated and integrated into the Crimean Karaite community but was not originally from Europe. Except for this man's paternal line, only East European Karaite lineages were tested. Some of our participants were children of mixed marriages between a Karaite and a non-Karaite. The women could only be tested on their maternal lines since the Y chromosome is not transmitted from fathers to their daughters."

Since "Karaite Jews mainly use descent through the male line as the way to determine a person's automatic Jewish or non-Jewish religious status[; t]he same used to be true of Rabbinical Judaism", and Ruth converted into Judaism via a levirate marriage to Boaz, for Karaites to have "married non-Israelite (Iberian, Italian, Indian, etc.) women" and have them convert was seen as perfectly fine. Also, prisoner-of-war women who chose to stay after a whole month converted into Judaism.

Also, women were usually not allowed to convert outside of Yahadut P'rushit—heck; they're not even allowed to be involved in sedarim l'Pesach, Torah and Talmud study, or donning of tefillin and tallitot in haredi communities: that's a "man's job", as the saying goes, in that community. After all, "[t]he rabbis are not concerned that women are not spiritual enough; rather, they are concerned that women might become too spiritually devoted". 

Monday, August 12, 2013

I Know What Anti Messianics and Self-Hating Jews Want--And It's Not Pretty!

Here's an example from "Slippery Sack"--who, if he is even a real Jew himself, surely doesn't act like one, anyway (Having treif pictures on your YouTube channel does not indicate taking your Jewishness seriously, for example.):

  • Slippery Sack 
    Nicole, You may not be Jewish at all, your family tree seems unconvincing, I am a real Jew, for example my family tree can be traced back to Abraham in an unbroken chain. Nicole it's OK if you are a Goyim. You seem to be trying to hard to be Jewish and quite frankly I'm not convinced.
  • Nicole Czarnecki 
    Not every Jew--especially many bnei-Anusim--have the luxury that you have. In fact, out of all people, Tracey R. Rich states that "So we see that Jewish genealogy is not as impossible as we might think. But it's not easy either. You are not likely to simply log onto Ancestry (or even JewishGen) and find a comprehensive tree listing your family back 300 years, as some gentiles do." She'd love for bnei-Anusim and Messianics like me to not identify as Jews.
     ·  in reply to Slippery Sack (Show the comment)
  • Nicole Czarnecki 
    Also, see "Claim: All Jewish genealogical records lost in 70CE". And we know that after the Galut b'Bavel ended, some could not trace their genealogy. "These sought their register, that is, the genealogy, but it was not found; therefore were they deemed polluted and put from the priesthood. 63 And the Tirshatha said unto them, that they should not eat of the most holy things, till there stood up a priest with Urim and with Thummim." (Ezra 2:62-63, cf. Nehemiah 7:64-65).
     ·  in reply to Slippery Sack (Show the comment)
  • Nicole Czarnecki 
    Also, not every genealogy of everyone is listed in Tanakh or Brit Chadashah. Therefore, your logic would assume that they didn't even exist, let alone be Jewish if they were Jews. Besides, many Messianic Jews took "But avoid foolish disputes, genealogies..." (Titus 3:9) out of context. After all, Yeshua had His genealogy recorded. Paul noted being a Binyamini. The context is in line with "For when one says, “I am of Paul,” and another, “I am of Apollos,” are you not carnal?" (1 Corinthians 3:4)
     ·  in reply to Slippery Sack (Show the comment)
  • Nicole Czarnecki 
    As John Gill commented, "and genealogies; of their elders, Rabbins, and doctors, by whom their traditions are handed down from one to another, in fixing which they greatly laboured; see ( 1 Timothy 1:4 )". Do we not see that now? e.g., "I am of Calvin--that is, a Calvinist." "I am a Lutheran." But what does Scripture say? "Be... of one mind...." (See 2 Corinthians 13:11) G-d doesn't contradict or change. Messianics, too, will have to consult our genealogies when the Beit HaMikdash is rebuilt.
     ·  in reply to Slippery Sack (Show the comment)

I even emphasized what Anti Messianics and Self-Hating Jews want, in case you did not feel like reading carefully and thinking for yourself.